Protein Details: Voltage-gated potassium channel subunit beta-1

Protein ID

ICDB_Pro_0883

Protein Name

Voltage-gated potassium channel subunit beta-1

Gene Name

KCNAB1; KVB3

Organism

Mustela putorius (European polecat)

Length

408 amino acids

AlphaFoldDB

AF-Q28528-F1-model_v4.pdb

Function

Sequence

MHLYKPACADIPSPKLGLPKSSESALKCRRHLAVTKPPPQAACWPARPSGAAERKFLEKFLRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

97;98;104;126;199;229;230;255;284;285;286;287;288;289;295;305;364;366;370;373;374

Disease

Location

Expression most abundant in aorta. Also high in left ventricle. Also detected in right ventricle; atrium; brain; skeletal muscle and kidney. Not detected in liver.

DOI ID

10.1074/jbc.270.11.6272